analysis uncovered that conolidine and cannabidiol drastically blocked Cav2.2 channels. In the peripheral and central nervous system, Cav2.2 channels can be found predominantly at presynaptic terminals32 and Participate in necessary roles in soreness perception by modulating depolarization-induced calcium entry into neurons33,34. Compounds that have an affect on presynaptic Cav2.2 https://emperorm516hxo2.signalwiki.com/user