Complicating drug interactions even further, lumacaftor is itself a solid inducer of CYP3A and may hence Restrict the efficacy of medications that happen to be cleared through this metabolic pathway. Specifically, the efficacy of hormonal contraceptives is impaired and substitute methods of contraception ought to be used in order to https://3-o-p-coumaroylquinic-aci33210.liberty-blog.com/28635811/detailed-notes-on-as1842856