There's a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-2-receptors while in the dorsal horn to minimize afferent pain transmission and deliver analgesia. As a result, medicine like clonidine that focus on alpha-2 receptors can affect the transmission of agony. Critical Allergic Reactions. Clonidine https://dickb702aws1.bcbloggers.com/profile