Genetic defects affecting the remethylation pathway cause hyperhomocysteinemia. Isolated remethylation defects are caused by mutations of the 5. 10-methylenetetrahydrofolate reductase (MTHFR) . methionine synthase reductase (MTRR) . https://www.jmannino.com/mega-grab-Cashel-Tail-Bag-top-buy/